CBD Oil Benefits and Side Effects
Recently, there have been a lot of big claims regarding the health benefits of CBD oil. Why did this compound suddenly capture the attention of so many people and the scientific community as well?
We’ll explore CBD oil benefits and side effects and how exactly it can help keep the body balanced and running normally.
What Does CBD Oil Stand for?
CBD is short for Cannabidiol, one of many naturally found compounds in the hemp plant. It interacts with our bodies' endocannabinoid system, which is in charge of homeostasis (state of steady internal conditions).
If you’ve heard about CBD, you have likely heard about a well-known psychoactive cannabinoid - THC. Both substances give the cannabis plant its medical and recreational properties. While marijuana has both THC and CBD in varying amounts, hemp contains practically no THC. This explains why consuming hemp-derived CBD oil benefits have nothing to do with feeling ‘high’.
But more importantly, CBD has a wide range of healing properties. The health benefits of CBD oil are not associated with a changed state of mind. Colloquially, it is even referred to as marijuana without the high".
CBD Oil Benefits List
Now that we know that CBD will not make you feel “trippy”, we can take a deeper look into the benefits of cannabidiol oil. Even though scientists have a lot to learn about the compound, the currently existing research overwhelming supports the healing claims. Here are the medical benefits of CBD oil backed up by multiple studies and clinical trials.
CBD for Various Types of Pain
There’s significant support for the health benefits of CBD oil such as alleviating pain. Some studies explore its general effect on pain sensitivity, while others can pinpoint an exact use for certain conditions.
The use of cannabinoids was shown to reduce chronic pain by affecting endocannabinoid receptor activity. As a result, the compound interacts with neurotransmitters and reduces inflammation.
To further explore that statement, one study focused on CBD injections for pain response. They found that systematically injected CBD induces a long-lasting effect, reducing incision pain in a model rat. Another study investigated the therapeutic potential of CBD on neuropathic and inflammatory pain. The results show reduced pain sensitivity to thermal and mechanical stimuli.
A recent trial showed CBD alone was effective in the treatment of knee osteoarthritis, and it also appears to be very safe for patients. CBD supplementation may be advisable for people with multiple sclerosis to reduce fatigue, pain, spasticity, and ultimately improve mobility.
CBD for Anxiety and Depression
What are the benefits of CBD oil for patients with anxiety and depression? CBD has shown anxiolytic effects both in humans and in animals.
For example, CBD significantly reduced anxiety, cognitive impairment, and discomfort in people with social anxiety disorders, according to a study. During a simulation public speaking test, people who had received CBD had better performance and were significantly less nervous before the performance.
Cannabidiol was also used for anxiety treatment in children with post-traumatic stress disorder. The results were overwhelmingly positive.
Several animal studies indicate that CBD has antidepressant-like properties. For instance, a particular trial identified effects that were comparable to those of imipramine, a tricyclic antidepressant. Another example is a trial focused on determining whether CBD reverses schizophrenia-related phenotypes. Results showed that subjects developed decreased anxiety-related behavior.
CBD for Insomnia
A CBD oil benefits list would be incomplete without mentioning its positive effect on sleep patterns.
Research published in 2019 explored whether CBD could improve sleep and or reduce anxiety. Sleep scores improved within the first month in the majority of test subjects but fluctuated over time. But overall, scientific evidence supports claims about a calming effect for CBD in the central nervous system.
Sleep disorders are often caused by mental health problems, such as anxiety, PTSD, and depression, and physical issues such as chronic pain. Therefore, by treating these conditions, CBD indirectly improves the quality of sleep. For example, this review points out significant improvement in the secondary outcomes of CBD, such as sleep and mood.
CBD for Cancer and Cancer Treatment Symptoms
There are CBD oil benefits for cancer as well as treatment-induced nausea, vomiting, and pain.
One groundbreaking study demonstrated CBD-induced cell death of breast cancer cells. This is the first step in exploring CBD treatment for an aggressive type of cancer. Also, the potential for anticancer properties is supported by another study on cancer progression. The researchers claim that CBD represents the first nontoxic external agent with such a powerful effect on metastatic breast cancer cells.
As for managing cancer treatment-related symptoms, this study looked at the efficacy and safety of the compound for such cases. The combination of CBD and other compounds was found to reduce chemotherapy-induced nausea and vomiting.
CBD for Acne
Research suggests that the benefit of CBD oil in reducing various types of acne is its ability to adjust how the body creates sebum, ab oily, a waxy substance in the skin. This study examined the effects of the administration of CBD to cultured human sebocytes. They found a significant inhibiting effect of CBD on humans and that it greatly reduces sebum production. Coupled with its antibacterial and antifungal effects, proven by another study, we can be confident in CBD oil benefits for the skin.
Findings from these studies also point to the benefits of CBD oil for other skin conditions: sensitive skin, eczema and psoriasis, age lines, and wrinkles.
CBD for Addiction
The United States is struggling with an opioid epidemic. There is currently an urgent need to find treatments for conditions normally treated with an opioid. Not only are there benefits of using CBD oil that can be used as a substitute for addictive medication, but it also has the potential to help people overcome addiction.
A group of researchers studied cannabidiol’s potential to prevent drug relapses. Their results provide sufficient evidence that supports this claim. First, it showed beneficial actions across several vulnerability states such as drug and alcohol addiction. Secondly, CBD can provide long-lasting effects after only a short period of treatment.
Another study indicates that CBD holds meaningful promise for treating people with heroin addiction. The individuals in the study received oral CBD and exhibited reduced drug cue-induced cravings.
CBD for Alzheimer’s
A study on long-term cannabidiol treatment showed that CBD could reverse cognitive deficits of AD (Alzheimer's disease) transgenic mice. Animal models that were treated orally for eight months exhibited an improvement in learning and less evidence of amyloid clumps in their bodies. CBD oil benefits for Alzheimer's are consistent with its anti-inflammatory benefits. Overall, it shows promise for AD preventative strategies.
This study is the first to demonstrate CBD's ability to prevent the social recognition deficit, but with such positive results, new studies will soon emerge.
CBD for ADHD
Traditionally, ADHD is treated with prescription drugs such as Adderall or Ritalin. These drugs successfully manage the symptoms of ADHD, especially in intense cases where there is no other treatment option available. However, there is a high risk of becoming addicted, especially considering that ADHD patients are prone to substance use and misuse.
With that in mind, CBD oil benefits for ADHD are becoming even more appealing. It does not have any addictive properties. Also, ADHD has been linked to anxiety and insomnia, which is what CBD can successfully combat, as seen in the studies above. The benefits of CBD oil are an overall calming effect, which is beneficial for people struggling with ADHD.
CBD for Diabetes
There is emerging research on CBD oil benefits for diabetes. For instance, experimental cannabidiol treatment was found to reduce early pancreatic inflammation in type 1 diabetes. The study revealed that the administration of CBD lowered incidences of diabetes in non-obese diabetic animal models.
There was another study in 2016, this time – on human subjects. Compared with baseline, CBD decreased resistin, an important link between obesity, insulin resistance, and diabetes. Therefore, the potential impact of CBD includes effects on cholesterol, glycemic control, and insulin sensitivity.
There are also suggestions on topical CBD oil benefits, which may aid in blood sugar control in type 2 diabetes via sprays.
Side Effects of CBD Oil
Luckily for CBD users, there is no evidence of toxicity or serious side effects, according to the World Health Organization report. Plus, it states that CBD exhibits no impact indicative of future abuse or potential dependence.
However, to be fully transparent, we should discuss some accounts of CBD oil side effects.
Possible Severe Adverse Reactions
One of the main risks of CBD oil is that it can lower blood pressure and interact with medication. It can affect the blood thinner Coumadin, which, in turn, can raise levels of other medication. While the change in coumadin levels will not affect a healthy person, it can be dangerous for someone with blood pressure issues.
The same report from Harvard Health publishing mentions that it can have the same effect as grapefruit juice. And although it is rare, the FDA warns that grapefruit can block the action of CYP3A4, an enzyme that breaks down medication. And that rather than being metabolized, a higher amount of that medication enters the blood. This means that if you consume large dosages of CBD and other medications, CBD may exacerbate the effects of the medication.
Mild Side Effects of CBD
According to a review on Cannabis and Cannabinoid research, the only CBD oil risks consumers might have to deal with are rare cases of tiredness, diarrhea/general sickness, and changes in appetite/weight. Let’s investigate these side effects and what you can do to prevent or subdue them.
It is not surprising that CBD can cause tiredness since it is widely used to treat insomnia. Mild drowsiness, in this case, should not be even considered an adverse effect but the desired effect. If you have to be alert or operate machinery, abstain from taking CBD right before or take a lower amount.
Diarrhea, nausea, or gastrointestinal problems might cause more discomfort. If you experience symptoms of indigestion, it might indicate that you don’t digest CBD oil well. This can happen with any oil or supplement. But a more plausible scenario would simply be the incorrect dosage. Since CBD is not FDA-regulated, there aren't any set doses so your calculations might be off. You read our guides on dosage depending on your weight, condition, and other factors.
The changes in appetite are specific to individual body chemistry.
In general, the Cannabis and Cannabinoid Research report emphasizes that in comparison with other drugs for the same medical conditions, CBD has a better side effect profile. As for specific types of consumption, it only depends on the concentration of the compound. For example, vaping CBD oil side effects are no more or less severe than a topical with the same dosage.
The Bottom Line
Early research on the benefits and side effects of CBD oil has shown encouraging results. However, the majority of clinical studies have been done on animal models or a relatively small number of human subjects. Therefore, larger studies and relevant legislation will provide better opportunities for prescribing CBD for the conditions mentioned above.
That said, the health benefits of CBD oil far outweigh the risks so you can start your journey to wellbeing right now. Once you gain a proper understanding of CBD, you can take advantage of its massive medical potential. Green Papas is here to help you with that. Our best-quality CBD oil and CBD-infused products will relieve uncomfortable symptoms, and you will be able to live your best life. Make your first purchase or restock on your previous batch and get it quickly delivered, right to your door.