CBD Effects on Brain
Cannabidiol (CBD) has been steadily growing in popularity, thanks to being able to impact the central nervous system. The compound shows promise at treating a range of problems – from anxiety to severe chronic pain – and in this article, we will go into detail about CBD effects on the brain. What conditions and diseases are affected by CBD? What is the link between CBD and serotonin? Does science support these claims?
By answering these questions, we get a better understanding of how the substance works and the impact of CBD on brain function.
CBD and Brain Fog
When it comes to stress-induced limited cognitive abilities and brain-fog, a common analogy is to think of your brain as a computer. Just like computers need to be shut down or occasionally paused, if you don’t do this and run the computer at high capacity, it will significantly decrease its performance. Similarly, if you don't take breaks, your brain is bound to malfunction at some point.
The first way that CBD helps with brain fog is by reducing the stress you endure on a daily basis. According to studies, CBD reduces negative symptoms in patients with a generalized social anxiety disorder. After investigating pathological anxiety and its underlying brain mechanisms, researchers concluded that an oral dose of CBD is successful in treating SAD. Subsequently, the less anxious a person feels, the more relaxed they feel in general.
Another reason to use CBD oil for brain fog is through its effect on the quality of sleep. CBD evens out sleep cycle dysfunctionalities by increasing the amount of time you are resting. This was confirmed by an animal study on the effects of acute systemic administration of CBD. For text subjects, REM (rapid eye movement) sleep latency increased, which lead to fewer disruptions of sleep continuity.
Insomnia is a usual byproduct of anxiety or chronic pain. CBD’s ability to manage anxiety and provide a great host of benefits comes in handy. You will maximize the relaxation your body and brain receive during sleep.
Overall, the use of CBD for brain fog is ensured by a combination of healing properties – from improved mood to alleviated pain.
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CBD and Serotonin
Serotonin affects multiple body functions – from your mood to your fine motor skills. This chemical or its low amount, to be precise, has been linked to various mood disorders, including anxiety and depression. CBD oil and serotonin remain an important topic of discussion, and researchers are discovering more information about the link between them.
Antidepressant and antipsychotic drugs target and regulate low serotonin levels. But adverse effects, drug interactions, and addictiveness of this medication make an argument in favor of using CBD to increase serotonin levels. Not only is CBD free from the drawbacks mentioned earlier, but it also is no less powerful in treating and managing anxiety, depression, insomnia, chronic pain, low self-esteem, and obsessive or negative thoughts and behaviors.
A study by the University of Rio de Janeiro suggested that CBD can replace serotonin. They concluded that this antidepressant-like and anxiolytic-like compound exhibits great psychiatric potential.
The topic of CBD and serotonin is mistakenly associated with serotonin syndrome. The reason is that typical medication for the same health conditions is known to cause this syndrome. By analogy, some people relate the same side effects to CBD as well.
Does CBD increase serotonin? Yes.
Can CBD cause serotonin syndrome? No.
CBD is not one of the drugs and supplements that can lead to serotonin syndrome. For example, drugs such as selective serotonin reuptake inhibitors, Zoloft, or Prozac; but only in high doses or taken together. Luckily for CBD consumers, there are no indications that link CBD and serotonin syndrome.
Further Research for Understanding CBD
There is still a lot of information about CBD effects on the brain to be uncovered. Even with the existing research, scientists can’t specify the mechanics of exactly how it helps. The best guess is through interacting with the endocannabinoid system (ECS) in various ways. However, the ECS is the body's most complex signaling system, and only further studies will fully describe CBD’s reaction with its receptors.
The reason for limited CBD research is that the legality of the substance has only been recently established. After the 2018 Farm Bill was introduced, it gave the green light to researchers. Therefore, we are likely to see advances in the understanding of CBD in the next couple of years.
Green Papas is dedicated to raising awareness about CBD and what CBD does to the brain. There is still unfulfilled potential, and our goal is to promote wellness through this natural yet powerful remedy. Our organic Kentucky-grown hemp undergoes a carefully executed extraction process to bring you the best product. Order high-quality CBD oils and experience the incredible effects first-hand.
How Does CBD Affect the Brain: Other Uses
As noted above, CBD offers many health benefits. Many of them are interlinked, meaning by improving one health condition, it ultimately helps another. Thus, along with improving brain health and cognitive performance, CBD helps with anxiety, depression, stress, sleep, and addiction.
Let’s examine in particular the effects of CBD on the brain and what scientific research has to say about it.
CBD Reduces Inflammation
Even though inflammation is supposed to clear damaged tissue and foreign substances, it also affects vital living tissues. Since our immune system is inclined toward inflammation, anti-inflammatory bodies and substances have beneficial properties for our bodies. This is one of the main points in favor of CBD oil.
CBD affects the migration and function of immune cells, which contributes to inflammation. Inflammation is triggered when immune cells cluster in specific locations of the body, and CBD helps inhibit this movement. For example, there is a therapeutic potential of CBD for brain damage. It has been suggested that brain inflammation aggravates brain damage and might even impact neurodegenerative diseases, including Parkinson's disease.
Neuroinflammation has been shown to affect signal transmission and network integration in the brain. Overactive inflammatory response, which is a common issue in many people, hinders important processes in the brain. For example, research linked neuroinflammation to decreased response capacity, inability to focus, and multitask, and both short- and long-term memory loss. Therefore, the use of CBD for brain healing is achieved through the diverse effect of anti-inflammatory responses.
One particular study investigated the effects of CBD on the cognitive and emotional impairments caused by cerebral hypoperfusion. Researchers learned that CBD could prevent cognitive and emotional impairments and stimulate neurogenesis. So, the topic of CBD and brain injury can be the next big breakthrough in CBD research.
CBD Impacts Neurotransmitters
Neurotransmitters transmit signals to and from your brain cells and play a major role in managing daily life and functions. The importance of neurotransmitters in brain health is not to be underestimated. For instance, they carry messages between neurons to regulate mood, sleep, memory, focus, behavior, etc.
In fact, when there's either too much or too little of certain chemicals, it can lead to various health complications:
- Mood affective disorders: depression, anxiety
- Fatigue, insomnia, adrenal insufficiency
- Cognitive fog, difficulty to concentrate and make decisions, ADD, ADHD
- Addiction and dependence
- Hormone imbalance
- Issues with appetite regulation
- Loss of appetite control
An animal study showed that CBD affects glutamate, a powerful excitatory neurotransmitter. Researchers confirmed that the administration of CBD significantly enhanced serotonin and glutamate levels in test subjects. Glutamate is responsible for vital brain functions, such as learning and memory, which is why further findings will make a big impact on a spectrum of brain disorders.
CBD Promotes Healthy Brain Cells
Experiencing certain changes in the brain function as you age is inevitable. Unfortunately, degenerative diseases of the brain are very prevalent now and are even expected to grow to affect 132 million people in 2050. However, there are ways to maintain brain function.
Structural and functional changes in the brain correlate to a variety of factors, including genetics and lifestyle decisions. But in addition to that, neuroplasticity and neurogenesis also play an important role.
The same study on neuroinflammation found that CBD helps strengthen existing connections between nerve cells. It also stimulates the process of giving birth to new neurons. This makes a strong argument for using CBD oil for brain health.
CBD Helps in Brain Cancer Therapy
Groundbreaking research on cannabinoids in glioblastoma therapy showed the potential of CBD oil for brain cancer. Glioblastoma (GBM) is considered the most destructive and dangerous form of solid cancer. Unfortunately, even aggressive treatment consisting of surgery and chemotherapy are unsuccessful – 95% of patients die within five years after diagnosis. There is a strong need to come up with new, advanced treatment vectors. Anti-tumor functions of CBD, which are indicated by the current evidence, point in the direction of using CBD for brain cancer.
The review of the latest findings demonstrates that CBD can reduce tumor growth, which is a substantial but righteous claim. Here is a more in-depth look into the data:
- Researchers found that CBD can inhibit cell growth and cell division, as well as the formation of new blood vessels.
- CBD can induce the uptake of dead tumor cells.
- They also noticed the ability to suppress the invasive nature of GBM tumors and the unlimited proliferation of stem cells.
- The survival rate of GBM patients went up after introducing CBD treatment.
These findings showcase CBD’s pharmacological effectiveness and make an important impact on cancer treatment. If the following research confirms and expands this knowledge, CBD oil could be widely used to treat brain tumors.
With such impressive results on CBD and brain tumors, imagine what the compound can do for less severe conditions and diseases. Green Papas consultants will be happy to help you find the right product to benefit your health. Visit our stores in:
- Albany, NY
- Middletown, NY
Or contact us online to get closer to a healthier, more comfortable life.
CBD Possesses Antioxidant Effects
Antioxidants prevent or slow stress to cells caused by a variety of factors, including environmental free radicals. Thus, they defend your cells from damage. Research on CBD shows therapeutic exploitation for its antioxidant properties. Researchers point out that CBD may have utility in treating many disorders associated with oxidative stress.
The absence of psychotropic side effects makes it a viable contestant for further drug development. Furthermore, CBD was shown to be more powerful than other substances with similar effects, such as ascorbate, alpha-tocopherol, vitamin C, and vitamin E.
CBD’s antioxidative, anti-inflammatory, and neuroprotection effects were also highlighted in a comprehensive review of clinical data. On top of the CBD benefits for brain health, it demonstrated physiological effects that promote and maintain overall health. Moreover, higher doses were shown to be well tolerated by humans and increase therapeutic effects.
CBD Improves Function in Alzheimer's Patients
With the growing body of research, the topic of CBD in the treatment and prevention of Alzheimer’s disease has been expanding as well. Studies reveal that CBD can reverse the cognitive deficits of AD transgenic mice. The teams focused on the evaluation of preventative properties after long-term use of the substance. And the results were promising – CBD reduced or removed the effect of inflammation, imbalanced oxygen levels, and a slight decrease in brain tissue.
Here is the in-depth explanation of what it means for AD treatment:
- Inflammation has a detrimental effect on the Alzheimer’s disease patient’s wellbeing. The inflammatory response occurs when the brain’s immune cells don’t clear disorienting blockages. This leads to confusion and memory loss. According to the study, CBD oil is capable of combating that.
- Oxidative stress is known to cause structural and functional abnormalities leading to Alzheimer’s disease. If brain cells release a lot of oxygen, it has a deteriorating impact on the patient’s health. Since CBD has powerful antioxidant properties, it can help mitigate the damage leading to AD.
- Lastly, people with AD exhibit a path of rapid brain cell decline and destruction. Research on the therapeutic properties of CBD summarized its ability to reduce damage in the nervous system. This means that CBD may have the ability to overturn or even prevent the various consequences of AD development. In the study, cognitive deficits in AD rodent models have been successfully reversed.
CBD Acts as an Anticonvulsant
Anticonvulsants, such as CBD, can prevent the spread of a seizure within the brain. Interestingly, the largest amount of information on CBD comes from epilepsy research. The investigation into anticonvulsant properties of CBD has even led to the FDA approving a CBD medication for this condition.
An important conclusion has been made as a result of a study on cannabidiol and sodium currents. Sodium channels trigger action potentials in brain neurons, and sodium channel blockers are known to help in epilepsy treatment. Therefore, since CBD is reported to regulate certain ion channels, including sodium channels, seizures can be reduced and minimized with the help of this substance.
A human clinical trial shows that CBD can improve seizure control in patients with specific epilepsy syndromes, particularly in children. Evidence concerning CBD’s potential anti-seizure efficacy reached a turning point in the last couple of years. More and more studies and personal accounts support this claim. Based on currently available information, it is fair to say that CBD can make a relative contribution to improved seizure outcome.
CBD Effect on the Brain: Conclusion
CBD addresses a variety of health and wellness problems. One of the biggest advantages of CBD compared to prescription medication is that it doesn’t have known side effects and is safe in large quantities. Also, it is not intoxicating or addictive. So, considering the remarkable findings of CBD and the brain, we will likely see a big change in the pharmaceutical industry.
Premium CBD products from Green Papas bring you positive effects in various forms: tinctures, edibles, topicals, and vape liquids. Whatever product you prefer; the quality of ingredients will always be up to the highest standards. Once you try our products and achieve the desired outcome, you will finally enjoy your life to the fullest!